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Venlafaxine
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Side Effect Registry
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Register new antidepressant side effects
here!
Side effects registered for Venlafaxine
The FDA has forced safety related drug labelling changes regarding
Efexor.
The changes acknowledge the existence of severe discontinuation
problems which are both dose and time related and that the evidence of the
problems has been obtained from a retrospective survey of the clinical trials
database.
This would tend to indicate, in our opinion,
that venlafaxine should be considered as a second line
antidepressant for resistant depression.
Caution should be used in the elderly, those at risk of CVAs
or the hypertensive.
- Withdrawal syndrome - sometimes severe
and prolonged. Characterised by:
- headaches
- nausea
- dizziness
- mood lability
- Gastrointestinal upset
- recurrence of depression
- bizarre dreams
- paraesthesiae
- auditory hallucinations
- Nausea
- Vomiting
- Dizziness
- Sexual dysfunction
- Hypotension
- Constipation
- Sweating
- Anxiety
- Convulsions
- Sleeplessness
- Palpitations
- Tremor
- Abdominal pain
- Rash
- Hypertension
About 40% of patients taking venlafaxine
suffer nausea and vomiting; thought to be dose related i.e. more
severe with higher doses.
See also Focus on Venlafaxine
and EffexorFX - private site
with side effects
Side Effect Registry: Antidepressants -
Overall Proportion of Registrations per Drug
Paroxetine
Fluoxetine
Moclobemide
Sertraline
Amitriptyline
References
Louie A K et al (1996) Venlafaxine Withdrawal
Reactions. Am.J. Psychiatry; 153:12,
165
Return to Registry
Last amended: 24/05/00
© Priory Lodge Education Ltd., 1994,1995,1996.
First Published: 1:41 PM on 10/Feb/96
Version 2.1